dedicated to vaccines

Influenza

Influenza facts

Frequently asked questions
More information

Influenza facts

Influenza or flu is an acute respiratory disease caused by a virus. It is also one of the most common diseases causing seasonal epidemics across the world every year.


The Influenza virus

Influenza viruses causing disease in humans are classified into two groups:

  •  Influenza A
  •  Influenza B.

Influenza A viruses are further classified into subtypes by Haemagglutinin (HA) and Neuraminidase (NA) proteins present on the surface of the virus particle.

Symptoms

Influenza infection is characterized by fever, muscle aches and respiratory symptoms such as cough, sore throat, sneezing and runny nose.

Most people recover completely within 1-2 weeks. However, Influenza may lead to severe complications such as pneumonia in infants, the elderly and immuno-compromised individuals.

Diagnosis

Respiratory symptoms during the flu season are indicative of Influenza. A definitive diagnosis requires laboratory confirmation.

Virus variations

Influenza viruses have the ability to change their genetic make-up by changes in the surface proteins by two different mechanisms.
Firstly, small changes, known as antigenic drift, occur frequently. The population is no longer completely immune to the virus and seasonal outbreaks of Influenza occur. These antigenic changes also require the annual reformulation of Influenza vaccines.
Secondly, Influenza A viruses may undergo major genetic changes known as antigenic shift. This results in a new influenza virus to which the human population is completely susceptible; an influenza pandemic may result.

Influenza vaccines

Annual vaccination helps to prevent Influenza infection.

Back to top

Frequently asked questions

How does the Influenza virus spread?
Influenza virus is found in the secretions of the respiratory tract. It is passed from person to person when infected individuals cough or sneeze. The Influenza virus enters through the nose and/or mouth. Multiplication of the virus takes place in the respiratory tract. Flu symptoms develop within 1-4 days after infection.

For how long is flu contagious?
An infected individual can spread the Influenza virus from the day before they begin to feel ill until 3-7 days after the start of flu symptoms. Children are able to transmit the virus for longer than 7 days.

Some people may be infected with Influenza virus but have no symptoms. During this time, they can still spread the virus to others.

Who should be vaccinated against Influenza?

  • Annual vaccination will reduce the chances of contracting flu.
  • Only children older than 6 months may be vaccinated.
  • Vaccination is strongly recommended for groups at high-risk of Influenza-related complications e.g. people older than 65. People in contact with these risk groups should also be vaccinated; this reduces the chance of exposure to Influenza for these groups.

How do I know if I have flu?
A sudden onset of fever, muscle aches and respiratory symptoms is indicative of flu. In the Northern hemisphere the flu season is November to April. Flu may however be contracted at any time of the year. Doctors can carry out tests in the first few days of illness to determine if you have flu.

Why do I have to be re-vaccinated annually?
The Influenza virus undergoes constant genetic changes. Each “flu season” the circulating virus is slightly different and you are no longer completely immune to it. The virus composition of the vaccines is adjusted annually to include the most recent circulating Influenza viruses.

Back to top

More information



Back to top

 
Nobilon influenza vaccine